Target oxidative stress-induced disulfidptosis: novel therapeutic avenues in Parkinson’s disease

Target oxidative stress-induced disulfidptosis: novel therapeutic avenues in Parkinson’s disease

Abstract Background Parkinson’s disease (PD), a globally prevalent neurodegenerative disorder, has been implicated with oxidative stress (OS) as a central pathomechanism. Excessive reactive oxygen species (ROS) trigger neuronal damage and may induce disulfidptosis—a novel cell death modality not yet...

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Bibliographic Details
Main Authors: Junshi Zhang, Tingting Liu, Haojie Wu, Jianshe Wei, Qiumin Qu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Molecular Brain
Subjects:
Parkinson’s disease
Oxidative stress
Disulfidptosis
Mitochondria
Online Access:https://doi.org/10.1186/s13041-025-01200-2
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https://doi.org/10.1186/s13041-025-01200-2

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