Recapitulation of physiologic and pathophysiologic pulsatile CSF flow in purpose-built high-throughput hydrocephalus bioreactors

Recapitulation of physiologic and pathophysiologic pulsatile CSF flow in purpose-built high-throughput hydrocephalus bioreactors

Abstract Background Hydrocephalus, an accumulation of cerebrospinal fluid (CSF) in the ventricles of the brain, is often treated via a shunt system to divert the excess CSF to a different compartment; if left untreated, it can lead to serious complications and permanent brain damage. It is estimated...

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Bibliographic Details
Main Authors: Ahmad Faryami, Adam Menkara, Shaheer Ajaz, Christopher Roberts, Ryan Jaroudi, Blake Gura, Tala Hussini, Carolyn A. Harris
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Fluids and Barriers of the CNS
Subjects:
Hydrocephalus
In vitro modeling
Cerebrospinal fluid flow pattern
CSF dynamics
Microfluidic
Pump
Online Access:https://doi.org/10.1186/s12987-024-00600-1
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https://doi.org/10.1186/s12987-024-00600-1

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