Short-Term Regulation of FcγR-Mediated Phagocytosis by TLRs in Macrophages: Participation of 5-Lipoxygenase Products

TLRs recognize a broad spectrum of microorganism molecules, triggering a variety of cellular responses. Among them, phagocytosis is a critical process for host defense. Leukotrienes (LTs), lipid mediators produced from 5-lipoxygenase (5-LO) enzyme, increase FcγR-mediated phagocytosis. Here, we evalu...

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Bibliographic Details
Main Authors: Carla da S. Pinheiro, Ana Paula T. Monteiro, Fabiano F. Dutra, Marcelo T. Bozza, Marc Peters-Golden, Claudia F. Benjamim, Claudio Canetti
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2017/2086840
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