Circ‐myh8/KAT7 Affects PANoptosis in Pulmonary Arterial Smooth Muscle Cells: Involvement of Super‐Enhancers in FOSL2 Expression

Circ‐myh8/KAT7 Affects PANoptosis in Pulmonary Arterial Smooth Muscle Cells: Involvement of Super‐Enhancers in FOSL2 Expression

Background Pulmonary hypertension is a pathophysiological condition characterized by multiple forms of regulated cell death. PANoptosis, which is an inflammation‐driven mode of regulated cell death, is regulated by the PANoptosome. Super‐enhancers (SEs) have been implicated in the pathology of pulmo...

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Main Authors: Jingya Zhang, Xinru Wang, Xu Wang, Songyue Li, Jianli Hou, Yibin Zhang, Xinyue Song, Shukun Cao, Ya Xu, Jing Qi, Baoshan Zhao, Xiaodong Zheng, Yan Xing
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
FOSL2
PANoptosis
pulmonary hypertension
super‐enhancer
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.040334
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https://www.ahajournals.org/doi/10.1161/JAHA.124.040334

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