HADHA-mediated regulation of JAK/STAT3 signaling in glioblastoma: a metabolic-epigenetic axis

Astract Glioblastoma multiforme (GBM) is one of the most aggressive forms of brain cancer, characterized by rapid growth and resistance to conventional therapies. This study investigates the role of HADHA, a key enzyme in fatty acid β-oxidation, in the progression of GBM. we show that the overexpres...

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Bibliographic Details
Main Authors: Kan Wang, Yifei Xiao, Jinxin Wan, Yuanqi Chu, Ruipeng Zheng, Fengjun Lv, Guang Yang, Mingchun Yang, Haitao Ge, Yuwen Song, Yu Cheng
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02660-0
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