The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach.

The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach.

<h4>Background</h4>Adiposity, assessed as elevated body mass index (BMI), is associated with increased risk of ischemic heart disease (IHD); however, whether this is causal is unknown. We tested the hypothesis that positive observational associations between BMI and IHD are causal.<h4...

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Main Authors: Børge G Nordestgaard, Tom M Palmer, Marianne Benn, Jeppe Zacho, Anne Tybjaerg-Hansen, George Davey Smith, Nicholas J Timpson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Medicine
Online Access:https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1001212&type=printable
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https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1001212&type=printable

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