A new therapeutic pathway in autoimmune diseases: chimeric antigen receptor T cells (CAR-T) targeting specific cell subtypes or antigen-specific B lymphocytes—a brief review

A new therapeutic pathway in autoimmune diseases: chimeric antigen receptor T cells (CAR-T) targeting specific cell subtypes or antigen-specific B lymphocytes—a brief review

In hematological malignancies, autologous immunotherapy with T lymphocytes expressing a chimeric antigen receptor (CAR-T) has been successfully applied. CAR enhances the immuno-cellular effector system directly against cells expressing target antigens. The objective here was to discuss the prospects...

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Bibliographic Details
Main Authors: María Fernanda Segovia, Diana Landoni, Yohana Defranchi, Rodrigo Calderón Jofré, Carlos A. Flores Olivares, Gerson D. Keppeke
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2025-03-01
Series:Exploration of Immunology
Subjects:
autologous immunotherapy
chimeric antigen receptor
chimeric autoantibody receptor
cytolytic lymphocytes
autoimmunity
autoantibodies
Online Access:https://www.explorationpub.com/uploads/Article/A1003185/1003185.pdf
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