Toward an integrated map of genetic interactions in cancer cells

Abstract Cancer genomes often harbor hundreds of molecular aberrations. Such genetic variants can be drivers or passengers of tumorigenesis and create vulnerabilities for potential therapeutic exploitation. To identify genotype‐dependent vulnerabilities, forward genetic screens in different genetic...

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Bibliographic Details
Main Authors: Benedikt Rauscher, Florian Heigwer, Luisa Henkel, Thomas Hielscher, Oksana Voloshanenko, Michael Boutros
Format: Article
Language:English
Published: Springer Nature 2018-02-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.15252/msb.20177656
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