Saliva as a potential diagnostic medium: DNA methylation biomarkers for disorders beyond the oral cavity

Saliva as a potential diagnostic medium: DNA methylation biomarkers for disorders beyond the oral cavity

Abstract Saliva is an accessible biofluid with potential for non-invasive disease diagnostics. This study explores how genetic susceptibility to common diseases is reflected in DNA methylation (DNAm) and gene expression profiles in saliva. We constructed cis-mQTL (n = 345) and cis-eQTL (n = 277) dat...

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Main Authors: Alba Hernangomez-Laderas, Ariadna Cilleros-Portet, Sergi Marí, Bárbara P. González-García, Ane Arregi, Alba Jimeno-Romero, Amaia Irizar, Iraia García-Santisteban, Corina Lesseur, Nora Fernandez-Jimenez, Jose Ramon Bilbao
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-025-00509-0
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https://doi.org/10.1038/s41525-025-00509-0

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