The causal effect of vitamin D binding protein (DBP) levels on calcemic and cardiometabolic diseases: a Mendelian randomization study.

The causal effect of vitamin D binding protein (DBP) levels on calcemic and cardiometabolic diseases: a Mendelian randomization study.

<h4>Background</h4>Observational studies have shown that vitamin D binding protein (DBP) levels, a key determinant of 25-hydroxy-vitamin D (25OHD) levels, and 25OHD levels themselves both associate with risk of disease. If 25OHD levels have a causal influence on disease, and DBP lies in...

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Main Authors: Aaron Leong, Waheed Rehman, Zari Dastani, Celia Greenwood, Nicholas Timpson, Lisa Langsetmo, Claudie Berger, METASTROKE, Lei Fu, Betty Y L Wong, Suneil Malik, Rainer Malik, David A Hanley, David E C Cole, David Goltzman, J Brent Richards
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1001751
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https://doi.org/10.1371/journal.pmed.1001751

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