Naloxegol to Prevent Constipation in ICU Adults Receiving Opioids: A Randomized Double-Blind Placebo-Controlled Pilot Trial

Background. Constipation is frequent in critically ill adults receiving opioids. Naloxegol (N), a peripherally acting mu-receptor antagonist (PAMORA), may reduce constipation. The objective of this trial was to evaluate the efficacy and safety of N to prevent constipation in ICU adults receiving opi...

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Bibliographic Details
Main Authors: Matthew S. Duprey, Harmony Allison, Erik Garpestad, Andrew M. Riselli, Anthony Faugno, Eric Anketell, John W. Devlin
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Critical Care Research and Practice
Online Access:http://dx.doi.org/10.1155/2022/7541378
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