Opposite effects of systemic and local conditional CD11c+ myeloid cell depletion during bleomycin‐induced inflammation and fibrosis in mice

Opposite effects of systemic and local conditional CD11c+ myeloid cell depletion during bleomycin‐induced inflammation and fibrosis in mice

Abstract Rationale Elevated levels of CD11c+ myeloid cells are observed in various pulmonary disorders, including Idiopathic Pulmonary Fibrosis (IPF). Dendritic cells (DCs) and macrophages (MΦ) are critical antigen‐presenting cells (APCs) that direct adaptive immunity. However, the role of CD11c+ my...

Full description

Saved in:
Bibliographic Details
Main Authors: Gabriel Augusto Oliveira Lopes, Braulio Henrique Freire Lima, Camila Simões Freitas, Andiara Cardoso Peixoto, Frederico Marianetti Soriani, Geovanni Dantas Cassali, Bernhard Ryffel, Mauro Martins Teixeira, Fabiana Simão Machado, Remo Castro Russo
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Immunity, Inflammation and Disease
Subjects:
CD11c
dendritic cell
fibrosis
macrophage
myeloid
α‐X integrin
Online Access:https://doi.org/10.1002/iid3.70042
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1002/iid3.70042

Similar Items