Nucleoid-associated proteins affect mutation dynamics in E. coli in a growth phase-specific manner.

The binding of proteins can shield DNA from mutagenic processes but also interfere with efficient repair. How the presence of DNA-binding proteins shapes intra-genomic differences in mutability and, ultimately, sequence variation in natural populations, however, remains poorly understood. In this st...

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Bibliographic Details
Main Authors: Tobias Warnecke, Fran Supek, Ben Lehner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002846&type=printable
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