A decisive technical leap forward for personalized medicine to treat mitochondrial diseases

Mitochondrial diseases, arising from mutations in mitochondrial DNA (mtDNA), are a diverse group of disorders that lead to severe conditions. Expression of mtDNA is a prerequisite for ATP production by oxidative phosphorylation. Individual cells contain many hundred copies of mtDNA and mutated mtDNA...

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Bibliographic Details
Main Authors: Abi S Ghifari, Martin Ott
Format: Article
Language:English
Published: Springer Nature 2025-04-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.1038/s44321-025-00232-4
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