Anti-microbial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase

Anti-microbial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase

Cetylpyridinium chloride (CPC) is a quaternary ammonium antimicrobial used in numerous personal care products, human food, cosmetic products, and cleaning solutions. Yet, there is minimal published data on CPC effects on eukaryotes, immune signaling, and human health. Previously, it was shown that l...

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Bibliographic Details
Main Authors: Bright Obeng, Lucas J. Bennett, Bailey E. West, Dylan J. Wagner, Patrick J. Fleming, Morgan N. Tasker, Madeleine K. Lorenger, Dorothy R. Smith, Tetiana Systuk, Sydni M. Plummer, Jeongwon Eom, Marissa D. Paine, Collin T. Frangos, Michael P. Wilczek, Juyoung K. Shim, Melissa S. Maginnis, Julie A. Gosse
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Journal of Immunotoxicology
Subjects:
Mast cell
tyrosine phosphorylation
cetylpyridinium chloride
Syk kinase
LAT
Lyn
Online Access:https://www.tandfonline.com/doi/10.1080/1547691X.2024.2443397
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https://www.tandfonline.com/doi/10.1080/1547691X.2024.2443397

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