Energy imbalance in oPOI ovarian granulosa cells is linked to reduced glucose bioavailability and metabolism

Energy imbalance in oPOI ovarian granulosa cells is linked to reduced glucose bioavailability and metabolism

Abstract Background Premature ovarian insufficiency (POI), affecting approximately 1% of women under 40, is associated with impaired fertility. Occult POI (oPOI), an initiating form, is more challenging to detect but still allows potential success with IVF. Recent studies suggest a possible link bet...

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Bibliographic Details
Main Authors: Weronika Marynowicz, Paulina Głód, Dawid Maduzia, Justyna Gogola-Mruk, Anna Ptak
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Reproductive Biology and Endocrinology
Subjects:
Occult premature ovarian insufficiency (oPOI)
Granulosa cells
Mitochondrial dysfunction
Energy metabolism
Glucose transporters
Online Access:https://doi.org/10.1186/s12958-025-01426-8
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https://doi.org/10.1186/s12958-025-01426-8

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