Antimicrobial, Synergistic, and Antibiofilm Activity of Sildenafil Against <i>Pseudomonas aeruginosa</i>: Preliminary Studies

Antimicrobial, Synergistic, and Antibiofilm Activity of Sildenafil Against <i>Pseudomonas aeruginosa</i>: Preliminary Studies

The present study tested sildenafil citrate as an example of pharmacological repositioning against the opportunistic pathogen <i>Pseudomonas aeruginosa</i>, known for its potent biofilm formation. We evaluated its antimicrobial, synergistic, and antibiofilm effects using broth microdilut...

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Main Authors: Thais de Moraes Barin, Camilla Filippi dos Santos Alves, Cristiane Antunes Teixeira, Camila Marina Verdi, Kelly Schneider Moreira, Thiago Burgo, Vitória Fernanda Belmonte Novais, Rodrigo de Almeida Vaucher, Roberto Christ Vianna Santos
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Applied Sciences
Subjects:
repositioning
sildenafil citrate
<i>Pseudomonas aeruginosa</i>
antimicrobial resistance
biofilm
Online Access:https://www.mdpi.com/2076-3417/14/22/10089
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https://www.mdpi.com/2076-3417/14/22/10089

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