Protein lipidation in the tumor microenvironment: enzymology, signaling pathways, and therapeutics

Abstract Protein lipidation is a pivotal post-translational modification that increases protein hydrophobicity and influences their function, localization, and interaction network. Emerging evidence has shown significant roles of lipidation in the tumor microenvironment (TME). However, a comprehensi...

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Bibliographic Details
Main Authors: Mengke Xu, Bo Xu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Molecular Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12943-025-02309-7
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