Comparison of localization and release of multivesicular bodies and secretory granules in islet cells: Dysregulation during type‐2 diabetes

Comparison of localization and release of multivesicular bodies and secretory granules in islet cells: Dysregulation during type‐2 diabetes

Abstract Multivesicular bodies (MVBs) are vesicles of endosomal origin containing intraluminal vesicles, which upon fusion with plasma membrane, secrete exosomes. They play a significant role in the physiology and pathology of type‐2 diabetes (T2D) due to disrupted intercellular communication. The r...

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Bibliographic Details
Main Authors: Priyadarshini Veerabhadraswamy, Kiran Lata, Sristi Dey, Prajakta Belekar, Lakshmi Kothegala, Vidya Mangala Prasad, Nikhil R. Gandasi
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Journal of Extracellular Biology
Subjects:
Pancreatic beta-cells
Exocytosis
Membrane trafficking
Metabolism
Online Access:https://doi.org/10.1002/jex2.70014
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https://doi.org/10.1002/jex2.70014

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