Lifetime estrogen exposure and domain-specific cognitive performance: results from the IGNITE study

IntroductionDisruptions in estrogen exposure (i.e., surgically induced menopause) have been linked to poorer cognitive aging and dementia risk. Hormone therapy use (e.g., birth control, menopausal hormone therapy) has shown mixed associations with cognitive performance, possibly due to limited cogni...

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Main Authors: Amber Watts, Shannon Donofry, Hayley Ripperger, Nicole M. Eklund, Lu Wan, Chaeryon Kang, George Grove, Lauren E. Oberlin, Swathi Gujral, Eric D. Vidoni, Jeffrey M. Burns, Edward McAuley, Charles H. Hillman, Arthur F. Kramer, M. Ilyas Kamboh, Kirk I. Erickson
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Aging Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1524474/full
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