Сасо-2 INTESTINAL PERMEABILITY AND Pgp-AFFINITY OF PHOSPHAZIDE

Сасо-2 INTESTINAL PERMEABILITY AND Pgp-AFFINITY OF PHOSPHAZIDE

In this work the intestinal permeability of phospazide in vitro was investigated using Caco-2 cell model in apical-basolateral (A-B) and basolateral-apical (B-A) directions as well as with the option of adding of P-glycoprotein (Pgp) inhibitor cyclosporine A. The following standard substances were u...

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Bibliographic Details
Main Authors: D. Yu. Grebenkin, Ya. M. Stanishevskiy, I. E. Shohin, A. M. Stoinova, M. A. Karpova, A. G. Koryakova, A. V. Ryabova, B. V. Brovchenko, A. A. Smirnov
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
bcs
permeability
caco-2
phosphazide
Online Access:https://www.pharmjournal.ru/jour/article/view/522
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https://www.pharmjournal.ru/jour/article/view/522

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