Copper supplementation enhances pigmentation and induces dopamine production in ARPE19.

Non-neuronal dopamine production has not been understood despite dopamine function in non-neuronal tissues. Tyrosinase is a non-neuronal enzyme which converts tyrosine to L-DOPA (l-3,4-dihydroxyphenylalanine) and L-DOPA to l-dopaquinone for further melanin production. Since L-DOPA is a dopamine prec...

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Bibliographic Details
Main Authors: Hironori Uehara, Baila Shakaib, Sangeetha Ravi Kumar, Bonnie Archer, Balamurali Ambati
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0327352
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