Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza.

Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza.

<h4>Background</h4>New prophylactic and therapeutic strategies to combat human infections with highly pathogenic avian influenza (HPAI) H5N1 viruses are needed. We generated neutralizing anti-H5N1 human monoclonal antibodies (mAbs) and tested their efficacy for prophylaxis and therapy in...

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Main Authors: Cameron P Simmons, Nadia L Bernasconi, Amorsolo L Suguitan, Kimberly Mills, Jerrold M Ward, Nguyen Van Vinh Chau, Tran Tinh Hien, Federica Sallusto, Do Quang Ha, Jeremy Farrar, Menno D de Jong, Antonio Lanzavecchia, Kanta Subbarao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS Medicine
Online Access:https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.0040178&type=printable
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https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.0040178&type=printable

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