Differential ER stress responses during lactation and postpartum outcomes in mice depending on their mitochondrial genotype

Abstract Breastfeeding protects against breast cancer in some women but not others, however the mechanism remains elusive. Lactation requires intense secretory activity of the endoplasmic reticulum for the production of milk proteins and endoplasmic reticulum- mitochondria contacts for lipid synthes...

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Bibliographic Details
Main Authors: Mrittika Chattopadhyay, Edmund Charles Jenkins, William Janssen, Thelma Mashaka, Doris Germain
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61666-5
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