In Silico study of PDE10A inhibitors for schizophrenia: molecular docking, ADMET and DFT analysis
Abstract Recently, interest in phosphodiesterase 10 A inhibitors has increased for schizophrenia treatment. Medicinal chemists have extensively worked on developing potent PDE10A inhibitors with minimal side effects. However, despite these efforts, PDE10A inhibitors have yet to gain approval for tre...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-06-01
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| Series: | Discover Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s44371-025-00234-8 |
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