Role of MicroRNAs in Chronic Myeloid Leukemia (CML) Treatment, Biomarkers, and Resistance to Tyrosine Kinase Inhibitor: A Bioinformatics-Based Analysis

Chronic myeloid leukemia (CML) is a myeloproliferative disorder caused by the reciprocal translocation of the BCR-ABL1 oncogene, which activates tyrosine kinase resulting in uncontrolled cell proliferation and apoptosis suppression. Although Imatinib (IM) is an effective treatment, IM resistance rem...

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Bibliographic Details
Main Authors: Syarifah Faezah binti Syed Mohamad, Rabiatul Adawiyah Ramlee, Marjanu Hikmah Elias
Format: Article
Language:English
Published: University of Brawijaya 2024-11-01
Series:Journal of Tropical Life Science
Subjects:
Online Access:https://jtrolis.ub.ac.id/index.php/jtrolis/article/view/3311
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