BCR-ABL gene amplification in patients with chronic myeloid leukemia and imatinib resistance

The treatment of Ph-positive chronic myeloid leukemia (CML) has achieved significant progress with the tyrosine kinase inhibitor (TKI) imatinib. Complete cytogenetic remission is a standard for patients treated in chronic phase. Nevertheless, primary and acquired resistance has been observed in few...

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Bibliographic Details
Main Authors: S. I. Kutzev, S. V. Mordanov
Format: Article
Language:Russian
Published: ABV-press 2022-11-01
Series:Онкогематология
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Online Access:https://oncohematology.abvpress.ru/ongm/article/view/777
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