Development of peptone-based serum-free media to support Vero CCL-81 cell proliferation and optimize SARS-CoV2 viral production

Development of peptone-based serum-free media to support Vero CCL-81 cell proliferation and optimize SARS-CoV2 viral production

Background: Developing an optimal media for Vero cell lines is crucial as it directly influences cell survival, proliferation, and virus production. The use of serum in cell culture raises safety concerns in biological production. The United States Food and Drug Administration (FDA) and the European...

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Bibliographic Details
Main Authors: Suryo Kuncorojakti, Diena Delaiah, Ahmad Aswin, Yulianna Puspitasari, Yeni Damayanti, Helen Susilowati, Diyantoro, Iwan Sahrial Hamid, Mohammad Anam Al Arif, Suwarno, Watchareewan Rodprasert
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Heliyon
Subjects:
Serum-free media
Protein hydrolysate
Vaccine
Manufacture process
COVID-19
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024171083
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