Identification of a novel subtype of SPP1 + macrophages expressing SIRPα: implications for tumor immune evasion and treatment response prediction
Abstract Background SPP1 + macrophages are among the major phagocytic cells, yet promoting tumor immune evasion and predicting unfavorable prognosis, in various cancer types. Meanwhile, the predictive value of the abundance of SPP1 + macrophages in patients receiving immunotherapy remains debatable,...
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| Main Authors: | Kun Chen, Yida Li, Jianjiao Ni, Xi Yang, Yue Zhou, Yechun Pang, Ruiting Ye, Hongru Chen, Silai Yu, Peng Wang, Zhengfei Zhu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-12-01
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| Series: | Experimental Hematology & Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40164-024-00587-3 |
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