Expression of the Metalloproteinase ADAM8 Is Upregulated in Liver Inflammation Models and Enhances Cytokine Release In Vitro

Acute and chronic liver inflammation is driven by cytokine and chemokine release from various cell types in the liver. Here, we report that the induction of inflammatory mediators is associated with a yet undescribed upregulation of the metalloproteinase ADAM8 in different murine hepatitis models. W...

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Bibliographic Details
Main Authors: Tanzeela Awan, Aaron Babendreyer, Justyna Wozniak, Abid Mahmood Alvi, Viktor Sterzer, Lena Cook, Jörg W. Bartsch, Christian Liedtke, Daniela Yildiz, Andreas Ludwig
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2021/6665028
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