A comprehensive map of the mTOR signaling network

A comprehensive map of the mTOR signaling network

Abstract The mammalian target of rapamycin (mTOR) is a central regulator of cell growth and proliferation. mTOR signaling is frequently dysregulated in oncogenic cells, and thus an attractive target for anticancer therapy. Using CellDesigner, a modeling support software for graphical notation, we pr...

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Bibliographic Details
Main Authors: Etienne Caron, Samik Ghosh, Yukiko Matsuoka, Dariel Ashton‐Beaucage, Marc Therrien, Sébastien Lemieux, Claude Perreault, Philippe P Roux, Hiroaki Kitano
Format: Article
Language:English
Published: Springer Nature 2010-12-01
Series:Molecular Systems Biology
Subjects:
cancer
CellDesigner
graphical notation
mTOR
regulatory network
Online Access:https://doi.org/10.1038/msb.2010.108
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https://doi.org/10.1038/msb.2010.108

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