Antibody-mediated spike activation promotes cell-cell transmission of SARS-CoV-2.

Antibody-mediated spike activation promotes cell-cell transmission of SARS-CoV-2.

The COVID pandemic fueled by emerging SARS-CoV-2 new variants of concern remains a major global health concern, and the constantly emerging mutations present challenges to current therapeutics. The spike glycoprotein is not only essential for the initial viral entry, but is also responsible for the...

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Main Authors: Shi Yu, Xu Zheng, Yanqiu Zhou, Yuhui Gao, Bingjie Zhou, Yapei Zhao, Tingting Li, Yunyi Li, Jiabin Mou, Xiaoxian Cui, Yuying Yang, Dianfan Li, Min Chen, Dimitri Lavillette, Guangxun Meng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011789
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https://doi.org/10.1371/journal.ppat.1011789

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