Protective role of RGS2 in PM2.5-induced ovarian injury in rats: Modulation of Gq/11 signaling to maintain granulosa cell [Ca2 + ]i stability
Fine particulate matter (PM2.5) is toxic to reproduction and can cause a range of reproductive disorders. However, the mechanisms underlying female reproductive impairment due to PM2.5 exposure are unclear. In this study, we aimed to investigate the effects of PM2.5 on rat ovaries and the underlying...
Saved in:
| Main Authors: | Zhenhua Ma, Xiaohui Du, Cuizhu Zhao, Yize Sun, Yunna Jia, Xiaojun Liang, Xiuzhen Yu, Yunhang Gao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
|
| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651325008826 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Attenuation of PM2.5-Induced Lung Injury by 4-Phenylbutyric Acid: Maintenance of [Ca<sup>2+</sup>]i Stability between Endoplasmic Reticulum and Mitochondria
by: Zhenhua Ma, et al.
Published: (2024-09-01) -
Regulation of FOXL2 gene in ovarian granulosa cell tumor by JNK inhibitor
by: Yuzhu Zhang, et al.
Published: (2025-04-01) -
Characterization of a novel IGFBP-2 transcript in the ovarian granulosa cells of chicken follicles: mRNA expression, function and effect of reproductive hormones and IGF1
by: Longxiao Hu, et al.
Published: (2024-12-01) -
Interactions between particulate matter and bacteria during cowshed PM2.5-induced respiratory injury initiates GBP2/Caspase-11/NLRP3-mediated intracellular bacterial defense and pyroptosis
by: Xiaohui Du, et al.
Published: (2025-07-01) -
Notch2 improves granulosa cell functions in premature ovarian failure by activating the Wnt2/β-catenin pathway
by: Xia Liang, et al.
Published: (2025-07-01)