A Versatile High‐Throughput Single‐Cell Screening Platform for Profiling Antigen‐Specific Long‐Lived B Cells in Blood and Bone Marrow

A Versatile High‐Throughput Single‐Cell Screening Platform for Profiling Antigen‐Specific Long‐Lived B Cells in Blood and Bone Marrow

Abstract Antigen‐specific B cells play a crucial role in the long‐term immune response following infection or vaccination, differentiating into antibody‐secreting cells (ASCs) and memory B cells (MBCs). However, profiling ASCs is challenging primarily due to their lack of membrane‐bound surface B ce...

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Bibliographic Details
Main Authors: Tian Zhao, Yuqing Lei, Chang Liu, Dong Zhang, Kaiyi Li, Sisi Shan, Chenyu Li, Zimeng Wei, Yuhan Yang, Ting Zhang, Kai Sun, Haoran Sun, Linqi Zhang, Peng Liu
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
antibody
B cells
high‐throughput
microarray
single‐cell sequencing
Online Access:https://doi.org/10.1002/advs.202414945
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https://doi.org/10.1002/advs.202414945

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