The first-in-Africa ex vivo drug sensitivity testing platform identifies novel drug combinations for South African leukaemia patient cohort

The first-in-Africa ex vivo drug sensitivity testing platform identifies novel drug combinations for South African leukaemia patient cohort

Abstract In South Africa, leukemia remains a major health concern, posing significant challenges in treatment due to its varied subtypes. There is an unmet need for a testing pipeline that can identify drug effects on patient samples in an ex-vivo setting. Using the pilot study with South African pa...

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Bibliographic Details
Main Authors: V. L. Kenmogne, M. M. Takundwa, E. E. Nweke, B. Monchusi, P. Dube, H. Maher, J. Du Toit, V. Philip-Cherian, P. N. Fru, D. B. Thimiri Govinda Raj
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Drug sensitivity test
Leukemia
Synergy
Full matrix combination
Online Access:https://doi.org/10.1038/s41598-025-93634-w
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https://doi.org/10.1038/s41598-025-93634-w

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