NLRP12 decreases TRIM25-mediated HK2 degradation to promote glycolysis and H3K18la in gastric cancer
Abstract Gastric cancer is the most common primary malignant tumor of the digestive system. Recent studies have shown that targeting tumor cell metabolic reprogramming is a key cancer treatment strategy. NLR family pyrin domain containing 12 (NLRP12) is related to innate immunity, inflammation and t...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-08-01
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| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-025-07923-3 |
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