miR‐322‐5p targets IGF‐1 and is suppressed in the heart of rats with pulmonary hypertension

Pulmonary arterial hypertension (PAH) is characterised by remodelling of the pulmonary vasculature leading to right ventricular hypertrophy. Here, we show that miR‐322‐5p (the rodent orthologue of miR‐424‐5p) expression is decreased in the right ventricle of monocrotaline‐treated rats, a model of PA...

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Bibliographic Details
Main Authors: Martin Connolly, Benjamin E. Garfield, Alexi Crosby, Nick W. Morrell, Stephen J. Wort, Paul R. Kemp
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12369
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