Distinct Omicron longitudinal memory T cell profile and T cell receptor repertoire associated with COVID-19 hospitalisation

Distinct Omicron longitudinal memory T cell profile and T cell receptor repertoire associated with COVID-19 hospitalisation

SARS-CoV-2 has claimed more than 7 million lives worldwide and has been associated with prolonged inflammation, immune dysregulation and persistence of symptoms following severe infection. Understanding the T cell mediated immune response and factors impacting development and continuity of SARS-CoV-...

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Bibliographic Details
Main Authors: Gavin Markey, Joseph McLaughlin, Darren McDaid, Seodhna M. Lynch, Andrew English, H. Denis Alexander, Martin Kelly, Manav Bhavsar, Victoria McGilligan, Shu-Dong Zhang, Elaine K. Murray, Taranjit Singh Rai, Colum Walsh, Anthony J. Bjourson, Priyank Shukla, David S. Gibson
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
COVID-19
T cell immunity
T cell receptor (TCR) recognition
antigen presentation
adaptive immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1549570/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1549570/full

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