Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for systemic inflammatory reactions

Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for systemic inflammatory reactions

IntroductionCritically ill patients suffer from a wide variety of clinical events, most of them leading to pro-inflammatory states such as sepsis or simply as consequence of major surgery. Many of these patients develop forms of acute kidney injury, heart or acute liver failure during intensive care...

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Main Authors: Holger Neb, Verena Roth, Jessica Roos, Tom Bauer, Anja Urbschat, Ulrike Heinicke, Carlo Angioni, Dieter Steinhilber, Matthias Piesche, Nerea Ferreirós, Robert Gurke, Gerd Geisslinger, Edith Utech, Kai Zacharowski, Patrick Meybohm, Patrick Paulus, Elke Schmitt, Thorsten Jürgen Maier
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
eicosanoids
prostaglandins
sphingolipids
ceramides
endocannabinoids
systemic inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1148806/full
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