Higher Rates of Viral Evolution in Chronic Hepatitis B Patients Linked to Predicted T Cell Epitopes

Higher Rates of Viral Evolution in Chronic Hepatitis B Patients Linked to Predicted T Cell Epitopes

The impact of hepatitis B virus (HBV) diversity and evolution on disease progression is not well-understood. This study aims to compare intra-individual viral evolution in two groups of chronic hepatitis B (CHB) patients, using antiviral treatment initiation as a measure of lack of immunological con...

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Bibliographic Details
Main Authors: Magnus Illum Dalegaard, Anni Winckelmann, Ulrik Fahnøe, Alexander P. Underwood, Anders Gorm Pedersen, Signe Bollerup, Jens Bukh, Nina Weis
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Viruses
Subjects:
HBV
next-generation sequencing
T cell epitopes
mutation rate
DANHEP
Online Access:https://www.mdpi.com/1999-4915/17/5/684
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https://www.mdpi.com/1999-4915/17/5/684

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