Brain diffusion tensor imaging changes linked to the split hand phenomenon in amyotrophic lateral sclerosis

Abstract The split-hand phenomenon is an early and specific feature of amyotrophic lateral sclerosis (ALS). This study aimed to investigate whether the split-hand phenomenon in ALS is associated with the white matter degeneration of the brain. Patients diagnosed with clinically definite or probable...

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Bibliographic Details
Main Authors: Seol-Hee Baek, Woo-Suk Tae, Dorothee Auer, Byung-Jo Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-97666-0
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