Dexmedetomidine Attenuates LPS-Stimulated Alveolar Type II Cells’ Injury through Upregulation of miR-140-3p and Partial Suppression of PD-L1 Involving Inactivating JNK-Bnip3 Pathway

Dexmedetomidine (DEX), which is reported to be a newly discovered, novel α-2 adrenoceptor agonist, is known to exhibit anti-inflammatory properties in several diseases. DEX regulates inflammation-related signaling pathways and genes through interactions with several miRNAs. This study verified that...

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Bibliographic Details
Main Authors: Xianfeng Chen, Juntao Hu, Jie Lai, Zhiyong Zhang, Zhanhong Tang
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2022/8433960
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