Imaging Collagen in Intact Viable Healthy and Atherosclerotic Arteries Using Fluorescently Labeled CNA35 and Two-Photon Laser Scanning Microscopy

Imaging Collagen in Intact Viable Healthy and Atherosclerotic Arteries Using Fluorescently Labeled CNA35 and Two-Photon Laser Scanning Microscopy

We evaluated CNA35 as a collagen marker in healthy and atherosclerotic arteries of mice after both ex vivo and in vivo administration and as a molecular imaging agent for the detection of atherosclerosis. CNA35 conjugated with fluorescent Oregon Green 488 (CNA35/OG488) was administered ex vivo to mo...

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Bibliographic Details
Main Authors: Remco T.A. Megens, Mirjam G.A. oude Egbrink, Jack P.M. Cleutjens, Marijke J.E. Kuijpers, Paul H.M. Schiffers, Maarten Merkx, Dick W. Slaaf, Marc A.M.J. van Zandvoort
Format: Article
Language:English
Published: SAGE Publishing 2007-07-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2007.00021
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https://doi.org/10.2310/7290.2007.00021

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