Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model
Background Accumulating evidence demonstrates that an increased tumor-associated macrophage abundance is often associated with poor prognosis in colorectal cancer (CRC). The mechanism underlying the effect of tumor-derived exosomes on M2 macrophage polarization remains elusive.Results The novel circ...
Saved in:
| Main Authors: | Yang Liu, Chen Chen, Jinbo Liu, Zhenqiang Sun, Bo Shao, Yanxin Xu, Pengyuan Dang, Shengyun Hu, Haifeng Sun, Chaoguan Wang, Junhong Hu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2024-05-01
|
| Series: | Journal for ImmunoTherapy of Cancer |
| Online Access: | https://jitc.bmj.com/content/12/5/e008491.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Identification of POLQ as a chromosomal instability-associated biomarker for hepatocellular carcinoma
by: Ying Cai, et al.
Published: (2025-11-01) -
POLQ mediated end-joining promotes DNA damage tolerance in neuroblastoma
by: Sahiti Chukkapalli, et al.
Published: (2025-08-01) -
CAFs exosomal circFOXO1 promotes TNBC autophagy and radioresistance via miR-27a-3p/BNIP3 axis
by: Xueqiong Xun, et al.
Published: (2025-08-01) -
Exosomal circRNA-0008302 from Adipose-derived Stem Cells Protects Against Myocardial Injury
by: Chengyan Hu, et al.
Published: (2024-02-01) -
Molecular epidemiological study of exosomes circZNF609, circPUM1, IGF2 with ischemic stroke
by: Suhai Fei, et al.
Published: (2025-03-01)