Codon Usage is Influenced by Compositional Constraints in Genes Associated with Dementia

Codon Usage is Influenced by Compositional Constraints in Genes Associated with Dementia

Dementia is a clinical syndrome characterized by progressive cognitive decline, and the symptoms could be gradual, persistent, and progressive. In the present study, we investigated 47 genes that have been linked to dementia. Compositional, selectional, and mutational forces were seen to be involved...

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Bibliographic Details
Main Authors: Taha Alqahtani, Rekha Khandia, Nidhi Puranik, Ali M. Alqahtani, Yahia Alghazwani, Saad Ali Alshehri, Kumarappan Chidambaram, Mohammad Amjad Kamal
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
dementia
GC composition
compositional constraint
codon usage
nucleotide skew
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.884348/full
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https://www.frontiersin.org/articles/10.3389/fgene.2022.884348/full

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