Interaction between Hormonal Receptor Status, Age and Survival in Patients with BRCA1/2 Germline Mutations: A Systematic Review and Meta-Regression.

Interaction between Hormonal Receptor Status, Age and Survival in Patients with BRCA1/2 Germline Mutations: A Systematic Review and Meta-Regression.

<h4>Background</h4>Germline mutations in the BRCA1 and BRCA2 genes are the most frequent known hereditary causes of familial breast cancer. Little is known about the interaction of age at diagnosis, estrogen receptor (ER) and progesterone receptor (PgR) expression and outcomes in patient...

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Main Authors: Arnoud J Templeton, Laura Diez Gonzalez, Francisco E Vera-Badillo, Ariadna Tibau, Robyn Goldstein, Boštjan Šeruga, Amirrtha Srikanthan, Atanasio Pandiella, Eitan Amir, Alberto Ocana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0154789
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https://doi.org/10.1371/journal.pone.0154789

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