Regulation of partial endothelial-to-mesenchymal transition by circATXN1 in ischemic diseases

Regulation of partial endothelial-to-mesenchymal transition by circATXN1 in ischemic diseases

Abstract Ischemic injury induces a partial mesenchymal shift in endothelial cells (ECs), contributing to impaired vascular regeneration. However, the molecular regulators of this transitional state remain poorly defined. To address this, we performed circular RNA profiling of endothelial cells under...

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Main Authors: Yue Li, Zhe Zheng, Yanze Li, Siyuan Fan, Lingyao Kong, Wanrong Fu, Zhonggen Li, Jianchao Zhang, Shuang Li, Zongtao Liu, Chao Liu, Jinhua Cao, Zhenxuan Hao, Lili Xiao, Youyou Du, Xiaofang Wang, Lu Gao
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61596-2
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https://doi.org/10.1038/s41467-025-61596-2

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