In situ treatment with a TLR9 agonist virus-like particle to promote immune responses against oral epithelial dysplasia progression

In situ treatment with a TLR9 agonist virus-like particle to promote immune responses against oral epithelial dysplasia progression

Abstract Leukoplakia, a common type of oral dysplasia, is simply defined as a white patch in the mouth or other mucosal surface. Oral dysplasia is the most common premalignancy in the oral cavity and yet it is insufficiently researched and thus both diagnosing and treating oral dysplasia are still p...

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Main Authors: Yan Xu, Alexandra Mcmillan, Nikesh Gupta, Caitlin D. Lemke-Miltner, Aseel O. Rataan, Sudartip Areecheewakul, Divya S. Bhat, Emily A. Lanzel, Sean M. Geary, Andrean L. Simons, George J. Weiner, Aliasger K. Salem
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Cancer Immunology, Immunotherapy
Subjects:
Oral epithelial dysplasia
Immunotherapy
Virus-like particle
Plasmacytoid dendritic cells
Online Access:https://doi.org/10.1007/s00262-025-04023-1
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https://doi.org/10.1007/s00262-025-04023-1

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