Src‐dependent phosphorylation of μ‐opioid receptor at Tyr336 modulates opiate withdrawal
Abstract Opiate withdrawal/negative reinforcement has been implicated as one of the mechanisms for the progression from impulsive to compulsive drug use. Increase in the intracellular cAMP level and protein kinase A (PKA) activities within the neurocircuitry of addiction has been a leading hypothesi...
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| Main Authors: | Lei Zhang, Cherkaouia Kibaly, Yu‐Jun Wang, Chi Xu, Kyu Young Song, Patrick W McGarrah, Horace H Loh, Jing‐Gen Liu, Ping‐Yee Law |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2017-08-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201607324 |
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