Src‐dependent phosphorylation of μ‐opioid receptor at Tyr336 modulates opiate withdrawal

Abstract Opiate withdrawal/negative reinforcement has been implicated as one of the mechanisms for the progression from impulsive to compulsive drug use. Increase in the intracellular cAMP level and protein kinase A (PKA) activities within the neurocircuitry of addiction has been a leading hypothesi...

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Bibliographic Details
Main Authors: Lei Zhang, Cherkaouia Kibaly, Yu‐Jun Wang, Chi Xu, Kyu Young Song, Patrick W McGarrah, Horace H Loh, Jing‐Gen Liu, Ping‐Yee Law
Format: Article
Language:English
Published: Springer Nature 2017-08-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.15252/emmm.201607324
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